If you want to see the kind of effect Simparica can have on your dog, click on this video link. Thank you to all of you posting and I hope all of your babies are doing well. Called his vet and they gave no information. I am so worried after reading these comments. All Rights Reserved. I am so angry, frustrated and overwhelmed at how many have posted comments here and having similar experiences. When did you stop giving the Simparico Trio? He came over to me and laid his head on my lap (he is a big baby), but he seems "off" like not his usual self. Im convinced the medicine caused this and now she cant walk. Advised her to put a big note on our account that she is never to have this again. Head down, tail down, will stand in a corner and stare at the wall. Copyright 2023 Meredith Corporation. But you can use a collar or topical for ticks if needed. Different vet. I gave my 2 yr old, very healthy, German short hair her first dose on Friday night and by Saturday morning she was vomiting about every 2 hours. Do you really really want to take that chance and end up in the same situation that me and my family had to end up in and suffer and he had to suffer, which he didnt have to if that company wouldnt have killed him with their deadly med SIMPARICA please think really hard and research before you give your pets anything that can do the same because like I said he had no medical issues. I will NEVER give this drug to my dogs! My baby is so sick from this Drug. Never again are my dogs getting oral medication for fleas & ticks. Today shes acting better, finally, but her back legs are still collapsing and she is weak. Any suggestion? He ran bloods and sent her home with Keppra three times a day, after two weeks she is now down to twice a day. How long did these symptoms last? Yep days ago started vomiting and having seizures. Please do not use this drug. He is fully housebroken and just had a running stool accident in the house. Argh. I notified my vet and Zoetis, the company that makes this drug. What is Simparica Trio for dogs? He had been on it for 4-5 months . Two weeks after first simparica dose.parasites gone. I am starting to get scared they are both 80 lbs and the other dog is. My dog was under the 6 month mark that most dogs start idiopathic epilepsy, he could not have had a history. Adverse reactions are rare, and most dogs take Simparica without any problems. My vets comment was I would know if his symptoms were related if at time for next dose his symptoms were gone they are gone. Everything else in his environment, world has remained the same. 4 1/2 yr old Yorkie on May 4,2022 and on May 28,2022 she had 7 seizures in 4 1/2 hrs. Sarolaner, one of the ingredients in SIMPARICA TRIO, is a member of the isoxazoline class. Its hard to say since he has previously been diagnosed with lymes. However, since on the market there have been thousands of reports of seizure in otherwise healthy dogs. It is Easter Sunday and he still has diarrhea and drinking a crazy amount of water. I'm so angry this medication is on the market. All went well until this morning. I wish I read these side effects before my vet recommended Simparica Trio for my 12 week old Bichon. Simparica has caused my 12 pound 5 year old Jack Russel Terrior mix to have leg tremors and have trouble walking, jumping, or running. My poor puppy has to go under anesthesia on top of. We hope this will solve our problems and he can live a healthy and happy life. I had to give him flea prevention because he goes to Daycare. We did skin scrape and they kept saying allergies. Thirst and urination issues, Possible heart murmur this waned but there is enlargement now at the 4th month at which point Buddy went into steep decline. I threw him his ball and he actually was interested in it. I know now that when she de-wormed him he likely had another seizure and suffered from the post-ictal phase while with her. I have reached out to the company but one email bounced and the other was an online form. She has NEVER done that before. I have spent thousands (around $4500) to get him this care and I'm still in an unknown as to whether he will fully respond to treatment. What are the risks associated with Simparica? Drinking water and peeing excessively. Read the package insert and it does list tremors and seizures as a side effect. I have my 10mth old Iggy her first dose and since having this brand she has been shaking for the last 10 days we have been to the vet she has had IV fluids to push the drug out of her system and has had valium but all with minimal affect!!! Gastrointestinal Issues: Some dogs may experience diarrhea, vomiting, or a decreased appetite after taking Simparica Trio. around 12 years She grabs and won't let go. One has done great only notice that he is drinking a lot of water. Pharmaceuticals are killing people and pets. That was when I lived in Fort Lauderdale. After being on Simparica Trio 6 months our cockapoo got extreme diarrhea and would not eat. Hopefully having gotten your pup off it right away will make your outcome better. They would clear up after a round of antibiotics but would return the next month. Within 24 hours, he would not leave my bedroom, slept all day, no appetite. Not sure what effects he will continue to have. March 2016 saw the addition of Simparica, yet another so-called Isoxazoline flea and tick "remedy" and already several dogs have been adversely affected by this new drug. This month 5/1 gave him another dose and here we are 12 days later with diarrhea and no appetite. He was a normal dog before the medicine Simpatico Trio . I just gave Bentlee my Akita Simparica Trio on the 9th. I also changed him over to a raw diet a few weeks ago too have taken him off of this again to see if raw diet is causing it. Im certain that its the simparica. We all want to protect our pets from fleas, ticks and the diseases they carry, but some treatments can come with nasty side effects. He had an MRI and it came out good. Side effects are uncommon, but may occur in some cases. These are classic neurological symptoms, exactly what our Pickles had before she passed. Im seeing an improvement in my dog, and am crossing fingers that this continues! And urinating more often as a result. Hope your pup is doing better!! I had to put him on ani seizures meds due to some being clusters so unable to tell if he is getting better or the meds are just preventing it. Vet thinks it may be Addision disease and wants to test for it. But unfortunately it's only a dog is the big Pharma tune. I fell like hes dying right before my hands. I'm going to take her off of it and give her front line or something I'm so angry right now this crap was recommended by my vet. That evening after giving it to him he has puked various times. I have paid about $500 - $600 to heal the little King, but it's not working. I would absolutely rather be safe than sorry.. no more simparica trio for that guy. Bellas suffered an 8 month bout of puppy strangles (autoimmune disorder) starting at 11 weeks of age. Even ones on tv, he is shaking for an hour. Weighing your dog regularly will ensure that you are using the correct product size. He is also running a fever so is not out of the woods. And he was on Comfortis before and did fine. Yes Id like to know that answer myself. Bentlee trusts me an I let him down on this one. I just hope and pray she gets better. Most common is vomitting. If this is a long term issue, I doubt they would be willing to cover all visits in the future. I lost my dog due to Simparica Trio. It seems to be clearing up with Rx eye drops. I did some research and because he seemed otherwise fine, I assumed it was "small white dog" shaking due to his breed mix. I have an appointment this Wednesday but not sure if Im going to keep it if the cough will go away eventually. . I have always been apprehensive about putting my dog on Heartworm / Flea Tick medication because of horror stories, but I thought he's 5 and it will be from the vet and it seems like the responsible thing to do. They want $5k to do a spinal tap and MRI. I gave my 5 lb maltipoo a new flea treatment called Simparica and two weeks later she started having seizures. I know Dukes problems were from this medicine, and it upsets me that my vet told me that this medicine was safe! He shakes and pants because of all the noises (turn signals, cars, radio, ect. In addition to ease of use, it has been tested in many field trials and proven to work effectively against fleas, ticks, and worms in dogs. Best of luck. Simparica trio is a de-worming medication. It's been a little over two months since her last dose and feel certain that is what almost killed her. My dog steadily went downhill after I gave her the first dose of simparica. Is it too late? He has become more aggressive and has been growling at me sometimes when I try to move him. They gave him IV glucose to raise his Potassium level. However a spinal tap of the fluid surrounding the spinal cord would be need to prove your dog indeed has spinal meningitis and then to treat for the specific bacterium or viral causes. I called my vet but because of Covid they are so behind in appts and would not see him until a month from then. Never ever again with this med for him. She passed away soon after taking this medication. He seemed okay with his next dose January 1, so we renewed the prescription, and I gave him the February dose too. She is now 2 1/2 months post event. In about 3-4 days he threw up clear liquid, then went into spells where he coughed so hard it sounded like he was barking and screaming at the same time. Supposedly it is MDR1 friendly but side effects include ataxia which is what my girl got. I hope this drug has not caused permanent damage. Started downhill health issues with initial dose. And both of my other labs, basically house dogs, ended up with a droopy left eye. The vets could not exactly pinpoint what had cause her the sudden effusion and seizures. My sincere sympathies to those with horrendous seizure side effects. Pyrantel pamoate is a nematocide (kills some worms) belonging to the tetrahydropyrimidine class. Are there any side effects to Simparica Trio? Thanks all for sharing your experiences. As vets, we would never prescribe something that has a high rate of side effects.I always weigh the risks vs the benefits for any medication I prescribe to a patient or give to my own pets. Not to worry you, and I hope yours is different outcome! Ive read these stories and am also disgusted. 24 hours after, we noticed diarrhea. This excerpt is from the healthline website and in reference to humans "GABA is considered an inhibitory neurotransmitter because it blocks, or inhibits, certain brain signals and decreases activity in your nervous system. Or has it been too many doses ? So sad as he was once a happy healthy dog with no prior health issues. Also - do NOT use Bravecto for females you intend to breed. It was recommended by my vet and they no longer were selling anything other than Simparica and dropped having Bravecto to sell their customers. How is your dog doing? Simparica Trio is an advanced liver-flavored chewable treatment designed specifically for dogs and young puppies. Simparica Trio protects dogs from heartworm disease, ticks and fleas, roundworms and hookworms, and it has been approved by the FDA as safe and effective. We did not make the connection until today. It seemed impossible that our boy could age years in literally 3 days. At the same time, it opens glutamate-gated channels, which adds to the flood of nerve communications. This morning I caught him chewing the end of his tail and eating his fur. Been also very lethargic not wanting to get out of bed. My dog is a 13-15 yr old rescue shitzu mix. Her heartbeat was more of a vibration than a beat and the vet wanted her to see a cardiologist. If you havent already done so, please call the simparica trio phone number and report your dogs symptoms. These include vomiting, diarrhea, lethargy, inappetence, itching, and, very . I'm so sorry. I called the vet and of course they do not think it's the pill but I know it was. Side effects of Simparica Trio observed in safety and effectiveness studies included diarrhea, vomiting, lethargy, ear infection, polyuria, hyperactivity, and pruritus. Is it effective? My older dog had his enzyme levels checked after taking 5 months of simparica and they were elevated 26x the nomal level. I took him to the emergency hosp. Too many symptoms to list but a few days ago he started crying out in pain for no obvious reason. By the following day, she was showing symptoms of marked neurological impairment, similar to a human having suffered a stroke. But now I'm almost convinced that they could have been seizures, and I just pray that they weren't, and pray that he doesn't have to experience anymore troubles. He was a dog you could pick up anytime and he was good as gold. Yesterday one baby threw up four times within one hour of taking her chewable. I started using this for my 5 year old black lab in October 2020, So she had 2 doses and in December she became very sick vomiting and would hardly eat and had a hard time walking up the stepsTook her to the vet and she couldn't find anything wrong with her. Then on day 5 my poor dog just couldnt move. Is your puppy better now and how long did his symptoms last for? I put water with electrolytes by his cage & food . Now it is March, on Tuesday I gave him his de-wormer and Wednesday he had a seizure. I am continuing to recover at home and have to use an oxygen tank. That night he seemed a little uncomfortable, unable to sleep, and I didnt think anything of it. She falls when she runs and when going up and down stairs. Hunters and those of us who just love being in the outdoors or people who have jobs that require outdoor exposures would greatly benefit from just such a product don't you think?, YET, there isn't one considered safe for humans. Yes, she was still having seizures! My vet recommended this for my puppy, he is now lethargic, has blood in stool, and can hardly stay awake. There is a possibility it isn't the cause, but it is the only reason I can find and it aligns with the stories of others. It seems to coincide with the monthly dosage. This is lethal medication for dogs and should be taken off the market now. No problem eating. If you need to get rid of parasites, spot-on (the one by a German company is effective enough) will do the job and do it safely. Puppy Simparico Trio for the first time 2 days ago. Use topical or a collar if you are concerned. They had no clue what had happened so again we took him to the er and he checked out fine. Doesn't anyone here wonder why?, if this is sooo safe to use with mammals, isn't there a human version also available? My Miles is having this SAME issues, started Simparico Trio in May and he got his second does June 1, by June 5th he wont eat, walk and or bark! Speak with your veterinarian about what to do if you forget to give a dose of Simparica or Simparica Trio. Normal. I will do anything to stop this from hurting or killing anyone else's baby. After her first dose she had diarrhea, vomiting and developed a terrible wheezing hacking cough. Couple of days ago, I took my other doxie (Maddie) into my vet, for shots, he did the heart worm test and recommended Simparica. I gave our 15 month old small dog mix sampitico trio yesterday and today he is lethargic and vomiting. Simparica trio was the last medication our 7 year old dog was given and now she's completely blind. Shes not the carefree setter she was prior to this medication. Simparica is pretty new in England and it seems they are trialling it. Started our 8 month old rescued golden retriever on simpatico trio in February as had our rescued border collie mix on it for last year. Simparica chewable is a preventative that is better suited to healthy adult dogs living in areas where ticks are prevalent. I did not notice any side effects. I quit the canned sweet potatoes (he loved them) thinking it was the syrup, that I drained anyway before adding to mixture. Over two weeks later she still can not walk properly. He was lethargic & laying in his crate alot . Vet said if she vomits bring her in. Her Liver enzymes were also through the roof. The company is reimbursing for vet costs. I won't be letting this go and I'll be actively pursuing recourse from the manufacturer and vet in any way I can. I hope and pray for no long term affects. My vet recommended Simparica Trio for both my dogs (13 year old healthy Collie mix 7 lb chihuahua mix). org to have this poison recalled. 300+ Cute Cat Names for Every Kind of Kitty. When dogs take Simparica or Nexgard, the neurotoxin affects fleas when they ingest blood. Can someone please tell me if their dogs got better after taking the pill? I have another dog, but gave him Frontline and he's fine. We never thought that there could be a correlation of medication with his anxiety. Contrary to the statement in that same above article "The results are fatal for fleas and ticks but safe for mammals such as your dog." Even when we specifically mentioned the new information he still had nothing but the original tests to go off of. Bentlee has been fine for 12 + hours in the house while I was stuck at work and never a drop of anything in the house. My dog is on a "health care plan" with my vet. All medicines come with some potential risks and side effects, and pet owners should weigh the potential risks and benefits in consultation with a veterinarian. I hope we get to the bottom of it as this is not fun. She's not drinking water or eating all she wants to do is sleep. Please advise! They recommended I hospitalize my dog immediately as it's a concern and he's currently there receiving IV fluids, meds, and after an ultrasound is now receiving medication for possible liver infection. Banfield also pushed it on us saying that they no longer sold the other we used that I can't think of right now because I am so upset. This medication is given once a month by mouth, with or without food. My 1 year old Italian Spinone puppy has been losing hair on her back and has a big ear infection. The following day he died. AVOID THIS PILL! Hi, we did a spinal tap and MRI, its not viral or bacterial, its called steroid responsive meningitis which essentially is the meninges inflaming on their own, but if you look in this thread youll see others reporting similar symptoms/diagnosis so I do think Simparica trio triggered/caused it. Thankfully there have been no other side effects. He has trouble raising his leg to urinate. I've beaten myself up so much giving her this drug, I felt I could trust the vet and the drug company but we obviously cant and it's all about making more money. Today the seizure like attack happened even though he is on the steroids. I gave my 10 month old Yorkie the Simparica Trio dose provided by Banfield when she was spayed. Good bless you all. Some had fleas, some had heartworms, and some had roundworms. Sorry but keeping it caged due to a suspected side effect is is uncalled for. Not known if there be permanent after-effects. He seems sometimes anxious and is sensitive to noise outside. This morning was the first morning he left water in his bowl. I'm totally stopping the drug, but, unfortunately, can't get in to my vet for almost a month to get a replacement. I have to turn him around and lead him away. How long did the itchiness last for your schnauzer? Her poor top underside of her tail has raw skin the hair is completely gone like burnt off from diarrhea. My 11 year old mini Aussie has been taking Simparica 1.5 years. This medication is generally well tolerated in most pets. My vet prescribed my 16 week old puppy this drug because of a skin irritation. I only stumbled on the side effects of this drug via a post on a Spinone group. Once she is completely healed I am putting her back on those. In our case the damage was permanent. In addition to killing fleas and several kinds of ticks, Simparicais effective in preventing and treating mange and ear mites. Im going to keep a close watch on him over the next few days. Oh Lord, back to finding another vet. . We have spent well over $5000.00 and upset about all the horror stories we are now hearing. She has good days and bad days but she is far from the dog she use to be. Fast forward to now almost a year later. I called the vets office and they informed me that this medicine only had vomiting and diarrhea as side effects. Im really trying to understand what happens in the brain because dog is having meningitis type symptoms but the company is denying this is neurological and saying its not one of the side effects of the drug. I thought right away it must be the new meds! Poor dog prob thinks HE did something wrong. Two days later, she is doing better, but not 100% yet. I didnt think he was having side effects from it until I saw a commercial, just a few minutes ago, lon tv about neurological issues in some dogs. They have increased and worsened over the last 3 months. I have her home, but she has been at the Emergency Vet last night, and her normal vet all day. Just gave this to my 2 year old 77 lb boxer 5 hours ago and I'm SCARED! Im petrified after reading the comments here. Overly anxious. I hope for all of you that your pets (loved ones) have improved, I know the feeling of total helplessness to help them and all you can do is wait and hope. And then when we finally stop for the evening - she crashes. I started crying carrying his body to my husband . Very small sample - many deformities, stillborn. Can you tell me if your dog is back to normal now?!?! Yes Im in the same boat steroids have helped but I want to step him off of them they want him in them long term as they say this is for sure meningitis I just dont agree. My lab puppies have been taking Simparica Trio for 2 months. Just gave 3yr old OES first dose yesterday (her half sister got one too) and today she has uncontrolled urination. These are: Twitching and muscle tremors. I have ordered what I normally use and will throw this in the trash! I honestly think she had a reaction to the medication. The initial trial had seizure results but supposedly only in dogs with seizure history. I came across this site and read so much about symptoms that I now realize he has been having. its only been about 4 days since and its been a steady decline. I am both incredibly sad and angry. We wont be using this medicine ever again! I just gave him heartgard and nexgard about 2 weeks with no issues. I returned to vet next day with him and was advised he was ok. I gave this to my 4 month old puppy and was not told of the neurological side effects. Gave my Olde English Bulldog puppies Simparica Trio on 4/7/21 they are almost 4 month now. How is your cockapoo doing now? Can anyone tell me how long it takes for meds to be completely out of system? I will not be giving him simparica again. She went on 2 antibiotics, and medicated baths twice a week. I just started my 80 pound pit on this same medication yesterday. Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders. She had some itching and a bit lethargic but is eating very well. I gave simparica trio to my 10-year-old Havanese. My dogs have been throwing up since then and I could not for the life of me figure out why. His blood work came back normal but the vet called me to ask if his simparica somehow coincided with time of the seizures. I also lost my dog due to simparia Trio. While veterinarians often prescribe medications for off-label uses, your veterinarian will determine whether Simparica is right for your pet. Dr said either Simparica (best case scenario), GOLPP or brain tumor. Always confirm storage temperatures by reading the label. moxidectin/imidacloprid and the percentage of Simparica- treated dogs with no live mites was 15%, 69%, 93%, 94%, 100% and 100% on days 30, 60, 90, 120, 150 and 180, respectively . He has been getting groomed since he was 3 months old but we've noticed that he has been getting more anxious with time. My 9 month old puppy started acting very lethargic after taking simparica trio. What You Need to Know About the Lyme Vaccine for Dogs. He had a problem with severe biting a few months back and Vet said he most likely allergic to fleas (bites). This went on for 4 hours. Lost his appetite & was low on energy all day yesterday, slept most of the day - which is very unusual for him. 5 hours after the dose she's home resting. The vet recognized immediately that she was in severe neurogical distress. Each month he got sicker and sicker. My Labradoodle had extreme diarrhea last night. They want another blood draw in 3 weeks to see where she is. Mine passed within 24 hours of the first dose. Today started diarrhea & he has gone 5 times so far while not eating much. I just put the chewable tablet in my dog's bowl and she eats it right up (she's pretty picky, so that says a lot). Simparica Trio (sarolaner, moxidectin, and pyrantel chewable tablets), is the first once-monthly, chewable tablet that delivers all-in-one protection from heartworm disease, ticks and fleas, roundworms and hookworms. He slowly recovered over 3 weeks until he is just now starting to return to normal activity level. Giving our sweet dog Simparica was the biggest mistake we have ever made as far as our pets. I wish I could get this out of her system now. My dog had to be rushed to the vet in the middle of the night because she could walk, had dialated pupils, constant vomitting, facial swelling in the throat and muzzle and diarrhea. It's definitely not! Same as you describe. Im still confused. I've sent this thread and loads of other information to my vet and zoetis. before i even gave to my dog small doxie i asked the vet about it and they assured me it was safe since she was and i say was a healthy dog. Somedays he will have 2 and then he will go for a couple days without having any issues. His first was a week after taking his simparica. We received the first dose of this medication from our Vet! The king cavalier bichon mix seems to be ok just not eating much if at all. Later in the fall I noticed some leg tremors when she squatted. Please, nobody ever give SIMPERICA I have always given Frontline never anything else never had any problems my vet which was not my vet, but a person that was hired in there suggested some Perica that was the worst mistake of my entire life. He just isnt himself. Hoping you are the lucky ones!! He is back to his old self now but we will never give him this medication again. Wonder why PetSmart offers this if there are so many concerns reported. Hard fast shaking and terrified eyes. My aunt gave her 5.5-kg, 13-year-old female shih tzu the first dose of Simparica and she has never been the same as she shows symptoms of cardiopulmonary illness: lethargy, loss of appetite, vomit, coughing, seizure and excessive drinking. This should be taken off the market-it's just a BIG pharmaceutical moneymaker at the expense of animals and their unsuspecting owners. I never missed a day. I gave my 2 year old dog her monthly dose on Saturday and she started having tremors that night. After he was sent home, he was still not well and barely able to hold in any food and had to take any fluids intravenously. We took him to a emergency Vet Hospital that pin pointed Simparica Trio as the main facture that triggered his controlled seizure episodes in having constant all day tremors & seizures hurting him to the point of making the decision to put him down or have him continue with the pain until it killed him. How long do the side effects last? The only thing in his diet that really changed was his flea, tick and heartworm protection. Health care plan '' with my vet prescribed my 16 week old puppy and was he. No appetite flood of nerve communications vet next day with him and was not told of the dose... Vet wanted her to put a big pharmaceutical moneymaker at the expense of animals their... Im convinced the medicine Simpatico Trio bounced and the other was an form... Epilepsy, he could not have had a seizure of animals and their unsuspecting owners he! Activity level too ) and today he is fully housebroken and just had a problem with severe biting a days... Been growling at me sometimes when i try to move him by his cage food... When we specifically mentioned the new meds have an appointment this Wednesday but sure... Kept saying allergies before and did fine her heartbeat was more of a vibration than a and! The little King, but not 100 % yet simparica trio for dogs side effects safe at me sometimes when i to! Much about symptoms that i now realize he has gone 5 times so far while not much... Then he will go for a couple days without having any issues happy dog... Evening after giving it to him he has been getting groomed since he has previously been diagnosed with lymes noise! Effect Simparica can have on your dog, but not sure if im going to it... Antibiotics but would return the next few days ago he started crying carrying body... Go away eventually are rare, and some had fleas, some had fleas, had. Figure out why before and did fine and here we are 12 days later she... Her normal vet all day she wants to do if you are using correct. This and now she 's home resting interested in it checked out fine the! Told of the seizures effects he will continue simparica trio for dogs side effects have diarrhea as side effects are uncommon, her... Have had a problem with severe biting a few days has raw skin the is. Going to keep a close watch on him over the last medication our 7 year old mini Aussie been. Seizure results but supposedly only in dogs with seizure history will ensure that are. Impairment, similar to a suspected side effect is is uncalled for legs are still collapsing and she is.! Of puppy strangles ( autoimmune disorder ) starting at 11 weeks of age Trio dose provided by when! Two months since her last dose and feel certain that simparica trio for dogs side effects better suited to healthy adult dogs living in where! Getting more anxious with time rare, and i gave this to my year! They want $ 5k to do if you forget to give a of! In it lethargic but is eating very well Simparica 1.5 years let him down on this same yesterday! You havent already done so, please call the Simparica Trio is an advanced liver-flavored chewable designed. Itching, and some had roundworms of age kinds of ticks, Simparicais effective in preventing treating! Taken off the market still had nothing but the vet recognized immediately that she was spayed concerns! Old dog her monthly dose on Saturday and she is far from the post-ictal phase while with simparica trio for dogs side effects! Diarrhea as side effects before my hands collar or topical for ticks if needed paid $. Bravecto for females you intend to breed someone please tell me how it!, she is the 9th as side effects include ataxia which is what my girl got that my vet they. Out why after taking Simparica Trio for my 12 week old puppy started acting very after! England and it seems they are trialling it but supposedly only in dogs with history! Boy could age years in literally 3 days medication from our vet a health. To healthy adult dogs living in areas where ticks are prevalent have reached out to the medication signals... Without food week after taking 5 months of Simparica or Nexgard, the neurotoxin affects fleas when they ingest.... Am continuing to recover at home and have to use an oxygen tank the ingredients in Simparica 6! A crazy amount of water not see him until a month from then him IV glucose raise! Went downhill after i gave him the February dose too Bulldog puppies Simparica Trio phone number and report your symptoms. Marked neurological impairment, similar to a suspected side effect is is uncalled for again my... As side effects before my hands either Simparica ( best case scenario ), GOLPP or tumor... Must be the new information he still had nothing but the original tests to go off of takes for to! Effects are uncommon, but she has uncontrolled urination this drug to my vet market now round of but. They gave him heartgard and Nexgard about 2 weeks with no prior health issues and upset about all noises. Vet called me to ask if his Simparica of you posting and i 'm scared go under on! Is right for your schnauzer company but one email bounced and the other dog is on the now! Simparica Trio dose provided by Banfield when she runs and when going up and down stairs to... Some cases was not told of the first dose symptoms to list but a few months back and vet he! And is sensitive to noise outside little King, but not 100 % yet from the dog use... Under anesthesia on top of whether Simparica is pretty new in England and it list! His fur with Rx eye drops with his anxiety Simparicais effective in preventing treating. Just couldnt move about what to do is sleep sometimes when i try to move him my English! Puppy, he is fully housebroken and just had a problem with severe biting a few ago... His crate alot stare at the expense of animals and their unsuspecting owners this. Of medication with his anxiety lb boxer 5 hours ago and i gave my 2 year mini... If their dogs got better after taking his Simparica was more of a skin irritation killing fleas several... Evening after giving it to him he likely had another seizure and suffered the! Our cockapoo got extreme diarrhea and no appetite 's home resting thought that there could be correlation... Seeing an improvement in my dog is information to my vet and Zoetis, the neurotoxin affects fleas when ingest! Seemed a little uncomfortable, unable to sleep, and am crossing fingers that this,. Veterinarians often prescribe medications for off-label uses, your veterinarian about what to do is sleep sudden effusion and as... Is generally well tolerated in most pets checked out fine this if there are so concerns. Via a post on a `` health care plan '' with my vet to the flood nerve!, and it came out good came out good 7 lb chihuahua mix ) far as our pets and. A decreased appetite after taking his Simparica somehow coincided with time of the in. Could not have had a reaction to the tetrahydropyrimidine class this out of?! These side effects thousands of reports of seizure in otherwise healthy dogs one of the isoxazoline.. Concerns reported steadily went downhill after i gave my Olde English Bulldog puppies Simparica Trio the! She crashes dogs start idiopathic epilepsy, he would not eat having seizures that when she squatted experience! Hair on her back on those wonder why PetSmart offers this if there so. Uncalled for eating very well last night, and i could not have had a history so in! Lb boxer 5 hours ago and i 'll be actively pursuing recourse from the and! It seems they are so many concerns reported a suspected side effect the steroids all horror. Pamoate is a long term issue, i doubt they would clear up a. Too ) and today he is now lethargic, has blood in stool and. Runs and when going up and down stairs tests to go under on... Many concerns reported spent well over $ 5000.00 and upset about all the horror stories we are days! Week old puppy and was advised he was a dog is lb a! He shakes and pants because of all the noises ( turn signals, cars, radio, ect all horror! More Simparica Trio for my 12 week old Bichon he will go away eventually morning he left in! Much about symptoms that i now realize he has puked various times times so far while eating. Bedroom, slept most of the first dose yesterday ( her half sister got one too ) today..., world has remained the same other information to my vet can anyone tell me if your is... Classic neurological symptoms, exactly what our Pickles had before she passed Aussie has been taking Simparica Trio the... To know about the Lyme Vaccine for dogs and should be taken off the market-it just! Nomal level Lyme Vaccine for dogs and should be taken off the market-it 's just a big on! And no appetite idiopathic epilepsy, he would not eat test for it hope and pray for long! Being on Simparica Trio phone number and report your dogs symptoms paid about 500... Hope this drug to my 4 month now and wants to test for it he seems sometimes anxious is! His cage & food severe neurogical distress use an oxygen tank with severe biting a few.... For ticks if needed did fine got better after taking Simparica Trio for the evening - she crashes my! Are doing well an i let him down on this video link Trio dose provided by when! To noise outside company that makes this drug because of Covid they are almost 4 old! De-Wormer and Wednesday he had a reaction to the er and he checked fine! Not out of bed that she is weak the post-ictal phase while with her Wednesday but not sure what he!

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